Obesity

Obesity is a chronic disease characterized by excessive accumulation of body fat that increases the risk of numerous secondary diseases. It typically develops through a combination of genetic factors, unhealthy diet, lack of physical activity, as well as hormonal and psychological influences. Obesity can be classified into different degrees of severity based on the extent of weight gain. The cardiovascular system, metabolism, and joints are particularly affected by obesity, which promotes diseases such as diabetes, high blood pressure, or arthrosis. Early diagnosis and targeted therapeutic measures are crucial to prevent health-related secondary diseases and maintain patients’ quality of life in the long term.
What is Obesity?
Obesity, commonly known as fatness, is a chronic metabolic disease characterized by an excessive increase in body fat percentage. Obesity also represents a significant health burden as it is considered an important risk factor for numerous chronic diseases. These include cardiovascular diseases, type 2 diabetes, stroke, and certain types of cancer. The development of obesity is usually multifactorial and can be influenced by a combination of genetic, social, and environmental factors.
The definition of obesity is often based on the Body Mass Index (BMI), which calculates body weight in relation to height. For years, BMI has been used as a rough guideline, but it is increasingly considered inadequate for a concrete diagnosis. BMI does not account for important factors such as muscle mass or fat distribution, which can lead to erroneous results. For example, a man with significant muscle mass may have a high BMI without being obese, while a person with a low BMI may still have health risks due to unhealthy fat distribution. Today, BMI is still widely used, but in combination with other measurement methods to create a more accurate picture of health risks. This classification of obesity serves not only as a basis for diagnosis but also for assessing potential risks associated with the disease. Obesity is a growing global problem, and its prevalence is drastically increasing in both developed and developing countries. Estimates suggest that about 13% of the world’s adult population is affected by obesity. Women are more frequently affected in many countries, which can be influenced by hormonal differences, such as estrogens, and societal factors. The development of obesity is often related to a combination of unhealthy diet, lack of physical activity, and genetic predispositions.
Obesity occurs in the population in various degrees of severity. The early stages, also called pre-obesity, are often less visible and can be characterized by slight weight gain or increased fat accumulation in the abdominal area. As weight continues to increase, the risk of serious health problems increases proportionally. Therefore, it is important to focus on early prevention and intervention.
Classification and Severity Levels
For the classification of obesity, the condition is divided into various severity levels defined by the Body Mass Index (BMI). The BMI serves as a measure to categorize overweight and obesity more precisely. The classification into different obesity grades also helps to better assess the risk of health complications and determine appropriate treatment options.
Pre-obesity
Pre-obesity refers to the transitional range between normal weight and obesity. Individuals with a BMI between 25 and 29.9 are considered overweight, but not yet obese. Although pre-obesity is not technically considered obesity, this condition can still increase the long-term risk of developing Grade 1 obesity. People with pre-obesity often do not yet have serious health problems, but they are more susceptible to secondary conditions such as high blood pressure or early metabolic disorders.
Obesity Grade 1
Obesity Grade 1, also known as mild obesity, is the first official grade of obesity. With a BMI between 30 and 34.9, the accumulation of body fat is already significantly increased. With this grade, initial health problems may already occur, including increased strain on the heart and circulatory system as well as a higher risk for the development of type 2 diabetes. Early intervention, such as changing eating habits and increasing physical activity, can help prevent the progression of the disease.
Obesity Grade 2
Obesity Grade 2, referred to as moderate obesity, has a BMI between 35 and 39.9. At this grade, the risk of serious health complications is considered significantly increased. The most common comorbidities include severe cardiovascular diseases, joint problems, and insulin resistance, which can lead to the development of diabetes. The health condition of those affected usually requires more intensive care, possibly also structured weight reduction or surgical interventions.
Obesity Grade 3
Obesity Grade 3, also known as morbid obesity, is the most severe form of obesity. People whose BMI is 40 or higher are therefore exposed to an extremely high risk of a variety of health problems. These include severe cardiovascular diseases, stroke, sleep apnea, joint degeneration, and various types of cancer. In many cases, conservative weight reduction is no longer sufficient, leading to increased consideration of procedures such as bariatric surgery to treat the condition and extend the lives of those affected.
Adipositas permagna
Adipositas permagna represents an extremely pronounced form of Grade 3 obesity and is characterized by an extremely high degree of overweight, often associated with a BMI of 50 or more. This form of obesity has enormous health implications and is therefore accompanied by severe physical and psychological impairments. Those affected suffer from severely restricted mobility and are frequently affected by other serious health problems.
Risk Factors and Causes of Obesity
The development of obesity is often complex and influenced by various factors. These can be of genetic, environmental, or psychological origin. A combination of these causes frequently leads to an imbalance between energy intake and expenditure, resulting in excessive fat accumulation in the body.
- Imbalance Between Energy Intake and Expenditure
- Genetic factors, family predisposition: Genetic predispositions can significantly influence the tendency to gain weight. A familial clustering of obesity usually indicates that certain genes can increase the risk of being overweight.
- Hormonal disorders: Disruptions in the hormonal balance, such as an underactive thyroid (hypothyroidism) or Cushing's syndrome, can significantly slow down metabolism and lead to weight gain.
- Environmental toxins: Certain environmental toxins, such as endocrine disruptors (e.g., Bisphenol-A) or heavy metals (like mercury, lead, cadmium), can cause hormonal imbalances in the body.
- Lifestyle
- Sleep deprivation
- Depressive disorders: Depressions are often associated with unhealthy eating behaviors that can lead to weight gain.
- Unbalanced nutrition
- Psychological factors such as eating disorders: Psychological conditions like binge eating disorder, where affected individuals uncontrollably consume large amounts of food, play a central role in the development of obesity.
- Medications: Certain medications, such as cortisone, psychotropic drugs, or medications for diabetes, can cause weight gain as a side effect.
This variety of causes illustrates that obesity is a very complex disease, often caused by multiple factors. Treatment must therefore be individually tailored and consider different approaches.
Obesity: Consequences and Complications
Obesity can have far-reaching effects on physical health and promote the development of a variety of chronic diseases. The consequences of this condition are not only physical in nature but also affect the psychological well-being and quality of life of those affected. Listed below are some of the most common and serious health consequences of obesity:
Cardiovascular Diseases:
Obesity increases the risk of serious cardiovascular diseases, such as heart attacks and strokes. Furthermore, excess weight puts strain on the heart and leads to increased blood pressure, cholesterol, and blood lipids, which increases the risk of atherosclerosis and other cardiovascular problems.
Type 2 Diabetes, Insulin Resistance:
People with obesity are often affected by the development of insulin resistance, which can significantly promote the onset of type 2 diabetes. This makes the body less sensitive to insulin, leading to elevated blood sugar levels.
Joint Degeneration such as Arthrosis:
Being overweight leads to increased stress on the joints, especially the knees and hips, which can accelerate cartilage wear. This often results in osteoarthritis and chronic joint pain.
Breathing and Sleep Problems:
Obese individuals often suffer from sleep apnea, a condition in which breathing stops during sleep. This leads to sleep disturbances, fatigue, and significantly reduces quality of life.
Fatty Liver:
An excessive proportion of body fat can lead to the accumulation of fat in the liver, resulting in fatty liver disease. This condition can lead to liver inflammation and cirrhosis in the long term.
Gallstones
Obesity promotes the formation of gallstones, as excess weight increases cholesterol production in the liver, which can lead to unhealthy gallbladder fluid.
Hormonal Dysfunctions:
Obesity also influences hormonal balance and can lead to disturbances in the endocrine system, which in turn affects metabolism, menstrual cycle, and fertility.
Infertility (especially in women):
Women with obesity often have a higher risk of suffering from infertility. Being overweight can lead to hormonal imbalances that impair ovulation and fertility through increased estrogen production.
Risk Factor for Cancer:
Psychosocial Consequences: Stigmatization, Depression:
People with obesity often face social stigmatization and discrimination, which can lead to psychological stress such as depression, anxiety disorders, and low self-esteem. These psychosocial effects are often as serious as physical health problems.
The effects of obesity are thus not limited to body weight but often affect the overall well-being of those affected. It is particularly crucial to recognize and treat obesity early to prevent the development of secondary diseases.
Obesity: Symptoms and Diagnosis
Obesity manifests in various symptoms that can be both physical and psychological in origin. Often, the disease initially goes unnoticed as it develops gradually. However, as excess weight progresses, health complaints can increase, significantly impairing quality of life. In the following, we want to explain the typical symptoms and diagnostic methods of obesity in more detail.
Obesity Symptoms
Obesity can manifest through a variety of symptoms that can significantly impact daily life. Generally, these complaints initially develop gradually and are therefore often noticed only when they severely restrict quality of life. The most common symptoms include:
- Fatigue and exhaustion: People with obesity often feel chronically tired and exhausted, as the body is under greater strain due to the additional weight, and sleep is frequently impaired by breathing disorders such as sleep apnea.
- Shortness of breath: Excess weight puts strain on the cardiovascular system and can restrict lung function, leading to shortness of breath, especially during physical exertion.
- Reduced mobility: The additional weight restricts mobility, making it more difficult to perform everyday activities such as climbing stairs or walking longer distances.
- Joint pain: Excess weight leads to greater stress on the joints, particularly the knees and hips, which can cause pain and, in the long term, joint degeneration such as arthritis.
- Digestive problems: Obesity can impair the function of the digestive system, leading to frequent gastrointestinal problems such as bloating, constipation, or heartburn.
- Excessive sweating: People with obesity often sweat excessively as the body has to expend more energy to regulate body temperature due to the additional body fat.
Diagnostic Procedures
The diagnosis of obesity usually involves a combination of different methods to comprehensively assess the health status of the affected person. The most important tool for evaluating overweight and obesity is the Body Mass Index (BMI), however, this alone is not sufficient to make a complete diagnosis. The BMI relates body weight to height and is calculated as follows:
BMI = Body weight (kg) / Height (m)²
However, BMI is not always an exact indicator of health status, as it provides no information about body composition, such as the proportion of muscle mass or fat tissue. For example, someone with a lot of muscle mass may have a high BMI without actually being obese. A significant part of the diagnostic process is therefore the medical history and physical examination. This includes gathering information about pre-existing conditions, nutrition and lifestyle, as well as family risk factors. Waist circumference and body fat measurements provide a more accurate assessment of how much of the body weight consists of fat. Various methods are used for this, such as skinfold measurements, bioelectrical impedance analysis, or dual-energy X-ray absorptiometry (DEXA).
Additionally, blood tests provide information about potential secondary diseases. Cholesterol and blood sugar levels are often determined to identify early signs of diabetes or cardiovascular diseases. Thyroid values are also frequently checked, as thyroid disorders can lead to weight gain. Furthermore, contextual factors such as blood pressure are measured. High blood pressure is often associated with obesity and represents an additional health risk. Other factors, such as hormone status and mental health, may also be considered as they can influence weight and metabolism.
Overall, a comprehensive diagnostic approach that includes physical measurements, laboratory tests, and contextual factors allows for a more accurate assessment of health risks when obesity is suspected.
Obesity Treatment
The treatment of obesity often requires an individualized and holistic approach, as the causes of the disease can be very diverse. Effective therapy considers both physical and psychological aspects and may include various therapeutic approaches. The choice of treatment depends on the severity of obesity, individual risk factors, and the health goals of the affected person.
A multimodal approach combines different therapeutic methods. A dietary change is often the first step to reduce caloric intake and learn healthy eating habits for the long term. The selection of nutrient-rich and low-calorie foods plays a crucial role in this process. Exercise is also essential to increase energy expenditure and maintain muscle mass. A regular exercise program that includes both endurance and strength training is considered ideal. Additionally, behavioral therapy is an important component of treatment to change unhealthy eating habits, identify possible emotional triggers for eating, and promote long-term motivation. In some cases, medication may be useful, especially when weight reduction through diet and exercise alone is not sufficient. A newer medicinal approach involves GLP-1 agonists, which reduce appetite, increase feelings of satiety, and stabilize blood sugar levels. These medications, sometimes known as “fat-loss injections,” have proven effective in supporting weight reduction but must be used in combination with a healthy lifestyle. A non-invasive approach for targeted fat reduction is cryolipolysis, where fat cells are specifically destroyed through controlled cold treatment. This method is particularly suitable for treating localized fat deposits that are difficult to reach through diet and exercise, such as on the abdomen or thighs. Cryolipolysis is a gentle, generally painless method, but it does not represent a long-term solution for comprehensive weight reduction. In severe cases of morbid obesity, surgical intervention may be considered. Two common surgical procedures are gastric reduction and gastric bypass. Both procedures aim to reduce the volume of the stomach to decrease food intake and achieve a feeling of fullness more quickly. These interventions can lead to significant weight reduction but involve risks and require long-term follow-up care.
The treatment of obesity should always be individually tailored and accompanied by continuous medical supervision to monitor potential side effects.
Holistic and Alternative Approaches
In addition to traditional medical approaches, there are a number of holistic approaches that can be used either alongside conventional treatments or depending on the cause of obesity. These approaches aim more specifically to consider the body as a whole and not just treat individual symptoms. They can provide supportive effects to improve quality of life.
Sources:
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6022277/ [EN]
- https://pubmed.ncbi.nlm.nih.gov/30180304/ [EN]
- https://pubmed.ncbi.nlm.nih.gov/33061498/ [EN]
- https://pubmed.ncbi.nlm.nih.gov/39112856/ [EN]
- https://pubmed.ncbi.nlm.nih.gov/26318445/ [EN]
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8124760/ [EN]
- https://pubmed.ncbi.nlm.nih.gov/32372444/ [EN]
Acupuncture and Naturopathy
Acupuncture is a traditional Chinese healing art in which fine needles are placed at specific points to harmonize energy flows and restore balance in the body. For obesity, acupuncture can help regulate appetite, support metabolism, and reduce stress. Naturopathy, on the other hand, uses herbal remedies and natural therapies to support weight reduction. Herbs such as green tea or ginger can stimulate metabolism, while other plants like willow bark have anti-inflammatory effects and can alleviate joint pain.
Sources:
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6022277/ [EN]
- https://pubmed.ncbi.nlm.nih.gov/30180304/ [EN]
- https://pubmed.ncbi.nlm.nih.gov/33061498/ [EN]
- https://pubmed.ncbi.nlm.nih.gov/39112856/ [EN]
- https://pubmed.ncbi.nlm.nih.gov/26318445/ [EN]
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8124760/ [EN]
- https://pubmed.ncbi.nlm.nih.gov/32372444/ [EN]
Yoga and Meditation for Stress Reduction
Another holistic approach is the use of meditation and yoga to promote physical flexibility and reduce stress. Chronic stress can increase cortisol levels, which can lead to weight gain or stagnation. Yoga promotes relaxation, strengthens the body, and reduces emotional burdens that often lead to unhealthy eating behaviors. Additionally, meditation helps calm the mind and develop a healthy relationship with food.
Orthomolecular Medicine: Iodine, Vitamin D3
Orthomolecular medicine deals with the targeted supply of micronutrients important for health. A deficiency in certain vitamins or minerals can negatively affect metabolism and lead to weight problems. Vitamin D3 and iodine, in particular, play important roles in fat metabolism and hormone regulation. Targeted use of dietary supplements can support weight reduction and improve general well-being.
Herbal Supplements
Herbal supplements such as green tea extract, chromium, or guarana are often used to support weight reduction. These substances reduce appetite, promote metabolism, and help stabilize blood sugar levels. However, they should always be used in consultation with a doctor or nutritionist to ensure they are appropriate for the individual situation and do not cause side effects.
Microbiome Therapy / Intestinal Cleansing
The microbiome, the microorganisms in the gut, plays a crucial role in digestion and metabolism. An imbalance in the microbiome can lead to weight gain and other health problems. Gut restoration includes measures to improve the intestinal flora, for example, by taking probiotics and prebiotics. These support the colonization of healthy bacteria in the gut and promote better digestion, which can positively affect body weight.
Sources:
These holistic and alternative approaches can meaningfully complement traditional therapies and help address obesity on multiple levels. They are particularly important when the causes of obesity are complex and involve emotional, hormonal, or psychological factors.
Obesity Treatment, Rehabilitation, and Long-term Care
In the treatment of obesity, rehabilitation and aftercare play a crucial role. Rehabilitation clinics specializing in obesity, support groups, and long-term therapies offer affected individuals comprehensive care that includes not only physical but also psychological support. In specialized rehabilitation clinics, patients are offered a holistic treatment program. Beyond nutritional counseling and exercise therapy, the treatment also includes psychological support to help patients implement long-term changes in their lifestyle. These clinics additionally monitor and treat medical comorbidities such as diabetes or hypertension. These programs are designed not only to promote weight reduction but also to improve health in the long term. After the initial therapy, support groups also provide valuable assistance. Here, those affected can share their experiences, motivate each other, and develop long-term strategies to maintain their new lifestyle.
Prevention
The prevention of obesity is of great importance to prevent the development of excess weight and associated health risks early on. Even in early adulthood, preventive measures can be taken to minimize the risk of obesity. Healthy nutrition, regular physical activity, good stress management, and adequate sleep hygiene play a central role in this. A balanced ratio of nutrients is fundamental to avoiding obesity. Reducing sugar and saturated fats in the diet helps stabilize body weight. Fresh, wholesome food rich in fiber, vitamins, and minerals should be prioritized. An active lifestyle is another important factor in preventing pre-obesity and obesity. Regular exercise promotes fat reduction, increases metabolism, and strengthens the cardiovascular system. Furthermore, excessive stress is another risk factor that can lead to unhealthy eating behaviors and weight gain. Stress management methods can lower cortisol levels in the body and reduce cravings for unhealthy foods. Additionally, healthy sleep hygiene helps stabilize weight. Too little sleep often leads to increased insulin sensitivity and hunger attacks, which can promote the development of excess weight.
Med. pract. Dana Hreus M.A.
Obesity can have various individual causes. The causal factors should be thoroughly clarified before treatment in order to achieve long-lasting success.

Frequently Asked Questions About Obesity
In the following, we aim to answer your most common questions about obesity to provide you with deeper insights into this condition.
Obesity is a chronic disease characterized by an excessive accumulation of body fat. It is typically defined using the Body Mass Index (BMI), with a value of 30 or higher being classified as obesity. Depending on the BMI, different degrees of severity are distinguished, from Grade 1 to Grade 3.
Obesity increases the risk of many chronic diseases, including type 2 diabetes, hypertension, cardiovascular diseases, and osteoarthritis. It can also lead to respiratory problems such as sleep apnea and increase the risk of certain types of cancer. In addition to the physical consequences, psychological burdens such as depression and social stigmatization may also occur.
In many cases, obesity can be significantly improved through long-term lifestyle changes, including healthy nutrition, regular physical activity, and behavioral therapy. However, complete cure is difficult as genetic, hormonal, and environmental factors often play a role. In severe cases, medical or surgical interventions such as gastric reduction surgery may be necessary to achieve lasting weight reduction.
Obesity is defined as having a Body Mass Index (BMI) of 30 kg/m² or higher. The BMI is calculated by dividing body weight in kilograms by height in meters squared. A precursor, known as pre-obesity or overweight, is defined as a BMI between 25 and 29.9 kg/m².
Yes, there are specific medications for treating obesity that can be used in combination with dietary changes and exercise. These include GLP-1 agonists, which increase the feeling of satiety and reduce fat absorption in the intestine. However, these medications should only be taken under medical supervision.
Yes, there are specialized treatment and rehabilitation programs aimed at long-term weight reduction and behavioral change. These are often conducted in specialized rehabilitation clinics and include combined therapies such as nutritional counseling, exercise therapy, psychological support, and medical monitoring. An obesity treatment program can help establish healthy habits, but it does not replace permanent lifestyle changes.
Obesity usually develops due to an imbalance between calorie intake and expenditure. This is often facilitated by unhealthy eating habits and lack of physical activity. In addition to lifestyle, genetic factors, hormonal disorders, certain medications, and psychological influences such as stress or eating disorders often play a role.
The German Obesity Society (Deutsche Adipositas Gesellschaft, DAG) is a scientific professional organization that focuses on researching, preventing, and treating obesity. It concentrates on scientific exchange, develops guidelines for therapy and prevention, and advocates for better care of affected patients. In Switzerland, there is the Swiss Obesity Foundation (Schweizerische Adipositas-Stiftung, SAPS).
Further information
The information listed contains relevant topics and serves to improve understanding.