Mitochondrial Disorders


Mitochondrial Disorders (mitochondriopathy) is a collective term for diseases in which the function of the mitochondria is impaired. The mitochondria are the energy producers of our cells. If they malfunction, a wide range of symptoms arise, such as muscle weakness, exhaustion, coordination problems, neurological abnormalities and organ failure.

Mitochondrial disorders can be congenital, meaning they can be inherited or acquired. The causes of congenital mitochondriopathies lie in genetic mutations of the mitochondria and their enzymes.

Acquired mitochondriopathies are mitochondrial dysfunctions that can be traced back to increasing damage to the mitochondrial RNA and mitochondria over the course of a lifetime. Chronic intoxication can play a decisive role in this.

Diagnosis and Causes of Mitochondrial Disorders

Mitochondrial disorders can be diagnosed with the help of an in-depth and detailed medical history in combination with special blood tests.

The various causes of mitochondriopathies can be:

  • Attack by free radicals in the cells (oxidative stress and nitrosative stress)
  • Mental and physical stress
  • Trauma to the cervical spine, e.g. after rear-end collisions (so-called cervical spine syndrome or cervical spine trauma)
  • Toxic stress
  • Disorders of the intestinal flora and intestinal diseases
  • Chronic inflammation and infections (EBV, Lyme disease)
  • Side effects of certain medications (e.g. statins, PPI)

Acquired mitochondrial dysfunctions, which result in insufficient energy supply to cells and organs, manifest themselves in mitochondrial neuro-, myo-, entero- and immunopathies.

Diseases from this group include, among others: allergies, asthma, arteriosclerosis, chronic fatigue syndrome (CFS), migraine, fibromyalgia, as well as neurodegenerative diseases (Alzheimer’s, multiple sclerosis, Parkinson’s).

Oxidative stress and nitrosative stress are significantly involved in the development of the above-mentioned diseases.

Dr. med. Karsten Ostermann M.A.

The treatment of people with mitochondriopathy requires a comprehensive and integrative approach by doctors and therapists from various disciplines. Individual counseling plays a decisive role in ensuring the best possible quality of life for those affected.

Dr. Karsten Ostermann

Further information

The information listed contains relevant topics and serves to improve understanding.